Piero, N.M.Njagi, J.M.Kibiti, C.M.Ngeranwa, J.J.N.Njagi, E.N.M.2013-09-242013-09-242012South Asian Journal of Biological Sciences, 2(2): 37-49.2249 - 6599http://ir-library.ku.ac.ke/handle/123456789/7341Diabetes mellitus is a metabolic disorder arising from deficiency of insulin by the pancreas or by the ineffectiveness of the insulin produced in the target cells. It is characterized by high levels of glucose in blood, which in turn damages many of the body systems particularly the blood vessels and nerves. This review explores the metabolic complications accompanying diabetes mellitus. It also provides a discussion of the pathogenesis of the complications of the disease. Key words: Diabetes mellitus, Insulin, Complications, PathogenesisenDiabetes mellitusInsulinComplicationsPathogenesisArticle