Kimani, ElishibaNdani, Mary N.2017-02-272017-02-272011Paper published with in the Global Education, Science, Technology and Public Policy Initiatives for Sustainable Development in Africa. Volume 1: 2011 Fall Edition, ISSN 2158-5598: 2158-558Xhttp://ir-library.ku.ac.ke/handle/123456789/15408Research PaperOne of the innovations that Kenyatta University (KU) adopted is the Open, Distant and e- Learning (ODeL) which involves students learning at a distance, using printed modules and interacting with lecturers through e-Learning. While this mode of learning has its advantages especially cost effectiveness and reaching many students, it has had challenges which have hindered its effectiveness and therefore the realization of its intended objectives. The main objective of the study was to identify the challenges faced by teacher-students enrolled for Bachelor of Education Degree in KU-ODeL, with a view of coming up with strategies to improve on the programme performance. The study sample comprised of 50% of the in-service teachers-students in KU-ODeL. Other respondents were the lecturers of the units offered through e-Learning. Statistical Package for Social Scientists (SPSS) was utilized for data analysis. The study concluded that the challenges to e-Learning programme generally fell into four categories, namely lack of time, inadequacy in ICT and computer skills, poor internet access and lack of proper and adequate equipments and soft ware. The study thus recommended that in addition to putting in place strategies to create more time for teacher-students and lecturers to engage in the e-Learning process, there is need to regularly build the capacity of both parties in ICT skills and explore ways of accessing affordable e-Learning facilitiesenKenyatta UniversityChallengesTeacher-Studentse-LearningArticle