Flaure, Rosette Ehawa EssoungaMba’ning, Brice MitterantTcho, Alain TadjongChhabra, Sumesh ChanderMohamed, Samira AbuelgasimLenta, Bruno NdjakouNgouela, Silvere AugustinTsamo, EtienneHassanali, AhmedCox, Russell John2020-10-052020-10-052020Flaure Rosette Ehawa Essoung , Brice Mitterant Mba’ning , Alain Tadjong Tcho , Sumesh Chander Chhabra , Samira Abuelgasim Mohamed , Bruno Ndjakou Lenta , Silvere Augustin Ngouela , Etienne Tsamo , Ahmed Hassanali & Russell John Cox (2020): Antifeedant and ovicidal activities of a new cassane and other compounds from Caesalpinia welwitschiana Oliv. and Caesalpinia bonduc L. against Tuta absoluta (Lepidoptera: Gelechiidae), Natural Product Research, DOI: 10.1080/14786419.2020.18254241478-6427https://www.tandfonline.com/doi/pdf/10.1080/14786419.2020.1825424http://ir-library.ku.ac.ke/handle/123456789/20520A research article published in Natural Product Research Formerly Natural Product LettersMethanolic extracts of liana of Caesalpinia welwitschiana and leaves of C. bonduc were found to possess moderate antifeedant and ovicidal activities against Tuta absoluta. Bioassay-guided isolation of constituents from the most active fraction of C. welwitschiana led to the identification of four known compounds [isobonducellin 1a and bonducellin 1 b, intricatinol 2, (-)-epigallocatechin-3-O-gallate 4] and one new constituent [welwitschianic acid 3]. The most active fraction of C. bonduc afforded two known constituents neocaesalpin L 5 and neocaesalpin A 6. The isolated structures were elucidated on the basis of their MS, UV, IR and 1 & 2 D NMR spectra and by comparison with literature data. Compounds 2, 4-6 were showed antifeedant and ovicidal properties against T. absoluta, some comparable to that of azadirachtin at 50, 100 and 200 ng/ml. Overall, the present study, conclude that the two species of the plant could be a promising source of ecofriendly botanical constituents.enCassanesflavonoidesTuta absolutaAntifeedantOvipositionCaesalpinia bonducCaesalpinia welwitschianaArticle