Ngugi, Mathew PieroNjagi, Joan MurugiKibiti, Cromwell MwitiMiriti, Phillip Mwenda2013-09-232013-09-232012Biochemical and Pharmaceutical Research, 1(2):375-381.2231-2560http://ir-library.ku.ac.ke/handle/123456789/7335Diabetes is a chronic disease with no cure (except experimentally in type I diabetics), but it can be managed effectively. Conventional management of this disease includes lifestyle modifications such as losing weight, diet and exercise to long-term pharmacological use of oral hypoglycemics and/or insulin therapy. This review explores the use of oral hypoglycemic agents in management of diabetes mellitus. Key words: Diabetes Mellitus, Oral Hypoglycemic Agents, Biguanides, Sulphonylureas, Meglitinides, Α-Glucosidase Inhibitors, Thiazolidinediones, Insulin TherapyenDiabetes MellitusOral Hypoglycemic AgentsBiguanidesSulphonylureasMeglitinidesΑ-Glucosidase InhibitorsThiazolidinedionesInsulin TherapyArticle