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Characterization of occult hepatitis B virus infection among HIV positive patients in Cameroon

Gachara, George; Magoro, Tshifhiwa; Mavhandu, Lufuno; Lum, Emmaculate; Kimbi, Helen K.; Ndip, Roland N.; Bessong, Pascal O. (BioMed Central, 2017)

Purpose: Occult hepatitis B infection (OBI) among HIV positive patients varies widely in different geographic regions. We undertook a study to determine the prevalence of occult hepatitis B infection among HIV infected ...

Non-Hepatic Adverse Effects of Antiretroviral Therapy for HIV Treatment and Care

Wambani, J.R.; Ogola, P.E.; Makori, A.W.; Rachuonyo, H.O.; Kiboi, N.G. (Adis, Springer Healthcare, 2016)

High-level viral replication occurs when HIV enters the body. Due to frequent mutations, the virus becomes resistant in the body and persists in memory T cells making it incurable. Lifelong therapy is then required ...

Oil Contents and Aflatoxin Levels in Peanuts Varieties Produced in Busia and Kisii Central Districts, Kenya

Menza, Nelson C.; Muturi, Margaret W.; Kamau, Lucy M. (OMICS International, 2016)

Busia and Kisii Central districts have repeatedly reported high levels of aflatoxins in foods. The objectives of the study were to determine oil contents and the relationship between oil contents and the levels of total ...

Potency status of oral polio virus vaccine among retrieved field samples in Kenya

Gachara, George; Hassan, J. A.; Mbugua, F.; Muchiri, J.; Symekhah, S.; Nakitari, G.; Borus, P.; Kamau, T.; Kombich, J. (Elsevier, 2014-04)

Background: In 1988 the World Health Organization (WHO) proposed mass immunization campaigns with the trivalent oral polio vaccine (TOPV) among children less than 5 years of age. The Vaccine Vial Monitor (VVM) is a small ...

Evolutionary Pattern of the Hemagglutinin Gene of Influenza B Viruses Isolated in Kenya 2005-2009

Gachara, George; Bulimo, W.; Magana, J.; Simwa, J.; Symekher, S. (African Journal of Health Sciences, 2011-06-17)

Background: In humans, the inability to provide lasting protection against influenza B virus infection is due, in part, to the rapid evolution of the viral surface glycoprotein, haemagglutinin (HA), which leads to a change ...

Human Bocavirus Infection in Children with Acute Respiratory Infection in Nairobi, Kenya

Gachara, George; Symekher, S.L.; Simwa, J.; Gichogo, J.; Rotich, M.; Ng’ayo, M.O.; Magana, J. (Scientific Research Publishing, 2013-12)

Background: Acute respiratory infection (ARI) is a leading cause of morbidity and mortality in children under five years of age in developing countries with viruses contributing significantly to this problem. The recently ...

Serotype and Genetic Diversity of Human Rhinovirus Strains that Circulated in Kenya in 2008

Milanoi, Sylvia; Ongus, Juliette R.; Gachara, George; Coldren, Rodney; Bulimo, Wallace (Wiley Open Access, 2016)

Background: Human Rhinoviruses (HRVs) are a well-established cause of the common cold and recent studies indicated that they may be associated with severe acute respiratory illnesses (SARIs) like pneumonia, asthma and ...

HIV type 1 drug resistance patterns among patients failing first and second line antiretroviral therapy in Nairobi, Kenya

Nyamache, A. K.; Koigi, P.; Ngayo, Musa Otieno; Khamadi, Samoel; Ngugi, Caroline (BioMed Central, 2014)

Background: The ever-expanding rollout of antiretroviral therapy in poor resource settings without routine virological monitoring has been accompanied with development of drug resistance that has resulted in limited treatment ...

Whole genome characterization of human influenza A(H1N1)pdm09 viruses isolated from Kenya during the 2009 pandemic

Gachara, George; Symekher, S.; Otieno, M.; Magana, J.; Opot, B.; Bulimo, W. (Elsevier, 2016)

An influenza pandemic caused by a novel influenza virus A(H1N1)pdm09 spread worldwide in 2009 and is estimated to have caused between 151,700 and 575,400 deaths globally.Whilewhole genome data on newvirus enables a deeper ...

Occurrence of Aflatoxigenic Aspergillus Species in Various Varieties of Peanuts Produced in Western Kenya

Menza, Nelson C.; Muturi, Margaret W.; Kamau, Lucy (PrePrints, 2017)

Aflatoxin contaminates foods including peanuts. Aflatoxin is a carcinogenic toxin mainly produced bty Aspergillus flavus. Other Aspergillus species that rarely produce aflatoxins are A. nomius and A. niger. Aflatoxin is ...