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Polymorphic Variability in the Interleukin (IL)-1Beta Promoter Conditions Susceptibility to Severe Malarial Anemia and Functional Changes in IL-1Beta Production
(PubMed, 2008-10)
Interleukin (IL)-1beta is a cytokine released as part of the innate immune response to Plasmodium falciparum. Because the role played by IL-1beta polymorphic variability in conditioning the immunopathogenesis of severe ...
Combining Evidence of Natural Selection with Association Analysis Increases Power to Tetect Malaria-Resistance Variants.
(PubMed, 2007)
Statistical power to detect disease variants can be increased by weighting candidates by their evidence of natural selection. To demonstrate that this theoretical idea works in practice, we performed an association study ...
Prevalence and Antimicrobial Susceptibility of Enterobacteriaceae Collected from Patients with Wounds at Kenyatta National Hospital
(2009)
Prevalence and sensitivity trends of Enterobacteriaceae isolated from septic wounds were determined through a prospective cross sectional study. One hundred and fifteen specimens isolated from in-patients in the Department ...