Show simple item record

dc.contributor.authorOkemo, P. O.
dc.contributor.authorMwatha, W. E.
dc.contributor.authorChhabra, S. C.
dc.date.accessioned2012-10-29T08:38:16Z
dc.date.available2012-10-29T08:38:16Z
dc.date.issued2004
dc.identifier.citationJournal of Tropical Microbiology Vol.3 2004: 88-94en_US
dc.identifier.issn1607-4106
dc.identifier.urihttp://ir-library.ku.ac.ke/handle/123456789/5854
dc.description.abstractBacteria are tested against antibiotics because of the resistance these bacteria show against known anti-microbial agents. Similar tests are done on plant extracts and isolated plant compounds. In this study, crude extracts of Ximenia caffra sond. (Ol acaceae) which were previously determined to have strong antibacterial activity were tested for the rate of killing bacteria in given time (kill kinetics). They were tested against strains of Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Candida albicans. Inoculated strains were tested against serial dilutions at time intervals of 0, 2, 4, 6, 8 and 24 h. Results obtained showed that X. caffra killed all S. aureus strains at 4mg/ml after 2h. Both 2mg/ml and 1mg/ml concentrations killed the same organism in 6 h. In comparison, the population of E. coli was reduced by a concentration of 8mg/ml from 2.03 ×106cfu/ml to 2.0 × 103cfu/ml in 24 h. C. albicans was killed by 8 mg/ml in 24 h. There was no effect on P. aeruginosa at all levels of the concentrations tested. It is concluded that the killing by X. caffra extracts is both time and concentration dependent and is cell wall related.en_US
dc.language.isoenen_US
dc.publisherAfrican Journals Onlineen_US
dc.subjectkill kineticsen_US
dc.subjectMueller Hinton Agar (MHA)en_US
dc.subjectXimenia caffraen_US
dc.subjectMinimum Inhibitory concentration (MIC)en_US
dc.subjectKilling curvesen_US
dc.subjectMinimum bactericidal Concentration (MBC).en_US
dc.titleThe kill kinetics of Ximenia caffra sond. (Olacaceae) extracts against selected bacteria and fungien_US
dc.typeArticleen_US


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record