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dc.contributor.authorKihampa, C
dc.contributor.authorNkunya, M.H.
dc.contributor.authorJoseph, C.C.
dc.contributor.authorMagesa, S.M.
dc.contributor.authorHassanali, Ahmed
dc.contributor.authorHeydenreich, Matthias
dc.contributor.authorKleinpeter, E.
dc.date.accessioned2012-10-19T11:58:38Z
dc.date.available2012-10-19T11:58:38Z
dc.date.issued2009-07
dc.identifier.citationPhytochemistry Volume 70, Issue 10, July 2009, Pages 1233–1238en_US
dc.identifier.urihttp://ir-library.ku.ac.ke/handle/123456789/5770
dc.description.abstractThe nor-halimane diterpenoid tessmannic acid and its methyl, 2-methylisopropyl and 1-methylbutyl esters, the unusual isocoumarins 8-hydroxy-6-methoxy-3-pentylisocoumarin and 7-chloro-8-hydroxy-6-methoxy-3-pentylisocoumarin, and 5-pentyl-3-methoxy-N-butylaniline were isolated from the stem and root bark extracts of Tessmannia densiflora Harms (Caesalpiniaceae) that showed mosquito larvicidal activity. The structures were determined on interpretation of spectroscopic data. Tessmannic acid and its methyl ester exhibited antibacterial and antifungal activity. The compounds also caused high larvae and adult Anopheles gambiae mosquitoe mortality effects, and stronger mosquito repellency than that shown by the standard repellent DEET, hence indicating Tessmannia species to be potential sources of bioactive natural products.en_US
dc.language.isoenen_US
dc.publisherElselvieren_US
dc.subjectTessmannia densifloraen_US
dc.subjectCaesalpiniaceaeen_US
dc.subjectNor-halimanoidsen_US
dc.subjectIsocoumarins anti-mosquitoesen_US
dc.subjectAntimicrobialsen_US
dc.titleAnti-mosquito and antimicrobial nor-halimanoids, isocoumarins and an anilinoid from Tessmannia densifloraen_US
dc.typeArticleen_US


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