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dc.contributor.authorLangata, Lydia Mali
dc.contributor.authorMaingi, John M.
dc.contributor.authorMusonye, Harry Asena
dc.contributor.authorKiiru, John
dc.contributor.authorNyamache, Anthony Kebira
dc.date.accessioned2020-10-28T07:15:58Z
dc.date.available2020-10-28T07:15:58Z
dc.date.issued2019
dc.identifier.citationLangata, L. M., Maingi, J. M., Musonye, H. A., Kiiru, J., & Nyamache, A. K. (2019). Antimicrobial resistance genes in Salmonella and Escherichia coli isolates from chicken droppings in Nairobi, Kenya. BMC research notes, 12(1), 1-6.en_US
dc.identifier.urihttp://ir-library.ku.ac.ke/handle/123456789/20699
dc.descriptionResearch Articleen_US
dc.description.abstractObjective: Increase in antimicrobial resistance is a threat to health sector globally. Surveillance on the spread and emergence of antimicrobial resistance is therefore invertible. This study investigated prevalence of Salmonella and Escherichia coli, molecularly characterized their antimicrobial resistance patterns and spread among resistant isolates from chicken droppings. Results: A total of 150 chicken households were selected randomly within Nairobi and fresh chicken droppings collected. Salmonella and Escherichia coli were isolated and antimicrobial susceptibility test carried out. Beta-lactamase genes and class 1 integrons were determined among amoxicillin resistant isolates. Isolates carrying TEM gene were further subjected to (GTG)5 PCR genotyping. Of the analysed samples, 57% and 12% contained Escherichia coli and Salmonella respectively. Most of the isolates were susceptible to the tested antibiotics with exemption of 53% of the isolates that were resistant to amoxicillin. The isolates were detected with TEM (46%), CTX-M (18%) resistance genes and class 1 integrons (25%). The study reveals presence of beta-lactamase genes and class 1 integrons across Salmonella and Escherichia coli isolates from droppings of reared chicken. Therefore, the wide distribution of chicken and their fecal waste is likely to increase development of antibiotic resistance.en_US
dc.language.isoenen_US
dc.publisherCross Marken_US
dc.subjectBeta-lactamase genesen_US
dc.subjectClass 1 integronsen_US
dc.subjectClonal expansionen_US
dc.titleAntimicrobial Resistance Genes in Salmonella and Escherichia Coli Isolates from Chicken Droppings in Nairobi, Kenyaen_US
dc.typeArticleen_US


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