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A Mathematical Model of Rabies Transmission Dynamics in Dogs Incorporating Public Health Education as a Control Strategy -A Case Study of Makueni County

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Date
2020
Author
Musaili, Jane S.
Chepkwony, Isaac
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Abstract
Rabies is a zoonotic viral disease that affects all mammals including human beings. Dogs are responsible for 99% of human rabies cases and the disease is always fatal once the symptoms appear. In Kenya the disease is still endemic despite the fact that there are efficient vaccines for controlling the disease. In this project, we developed SIRS mathematical model using a system of ordinary differential equations from the model to study the transmission dynamics of rabies virus in dogs using public health education as a control strategy. The reproduction number R0 was calculated using the Next Generation Matrix. Both disease free and endemics equilibrium points were determined and their stability analysis performed. From the stability analysis results it was found out that the disease free equilibrium point is both locally and globally asymptotically stable when R0 < 1 and the endemic equilibrium point is both locally and globally asymptotically stable when R0 > 1. Numerical simulations done using Matlab indicated that education of the public on administration of both pre and post exposure vaccines to dogs and responsible dog ownership
URI
http://ir-library.ku.ac.ke/handle/123456789/20149
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