Show simple item record

dc.contributor.authorNjangiru, I.K.
dc.contributor.authorGitimu, M.R.
dc.contributor.authorNjagi, E.N.M.
dc.date.accessioned2017-12-29T07:28:37Z
dc.date.available2017-12-29T07:28:37Z
dc.date.issued2017
dc.identifier.citationJournal of Medical Biomedical and Applied Sciences volume 5 issue 1 2017en_US
dc.identifier.issn2349-0748
dc.identifier.urihttp://ir-library.ku.ac.ke/handle/123456789/18019
dc.descriptionResearch Articleen_US
dc.description.abstractIntroduction: Psidium quajava has for long been employed in the management of many diseases in Kenya, including diabetes mellitus. However, the use of this plant extract lacks scientific validation in regard to its efficacy. This study aimed at investigating in vivo antidiabetic activity of aqueous extract of Psidium quajava in alloxanized diabetic mice. Antidiabetic property was assessed through oral and intraperitoneal administration of aqueous plants extract at doses of 50, 100, 200 and 300mg/kg body weight and profiling the levels of blood glucose after 0, 1, 2, 3, 4, 6 and 24 hours using a glucometer. The mineral composition of the aqueous plant extract was assayed using Total Reflection X-ray Fluorescence system (TRXF), while the different types of secondary metabolites were assessed using standard procedures. The aqueous plant extract exhibited a dose dependent hypoglycemic activity in alloxanized diabetic mice. The studied plant extract contained alkaloids, flavonoids, saponins, tannins, and total phenols at varying concentration. The mineral profile demonstrated the presence of detectable levels of K, Ca, Ti, V, Mn, Fe, Ni, Cu, Zn and As. The plant’s aqueous extract was effective in lowering blood glucose levels.en_US
dc.language.isoenen_US
dc.publisherManuscript Centralen_US
dc.subjectDiabetes mellitusen_US
dc.subjectPsidium quajavaen_US
dc.subjectAntidiabeticen_US
dc.subjectAqueous extracten_US
dc.titleIn Vivo Antidiabetic Activity of Aqueous Extract of Psidium Quajava in Alloxanised Diabetic Miceen_US
dc.typeArticleen_US


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record