Complement system, an important component of the innate and adaptive immunity, is over activated during malaria infection. As a result, components of the cascade are utilized consumed and this has the potential to impair ...

Pyridoxal kinase (PLK: EC2.7.1.35) is an essential enzyme for cellular synthesis of proteins where it plays a central role in transamination reactions. PLK is required for biosynthesis of B-6 coenzyme in which it ...

Malaria is a major cause of morbidity and mortality in sub-Saharan Africa. Most of the mortality is the result of severe infections that occur in a small proportion of individuals, mostly children and pregnant women. A ...

Deficiency of Glucose-6-phosphate dehydrogenase (G6PD) is the most frequently encountered genetic abnormality of red blood cell (RBC) metabolism, and is estimated to affect over 200 million people worldwide. Malaria is ...

Malaria imposes a huge burden upon the health and economic development of tropical nations and has been identified as a major obstacle to sustainable development by the world's poorest regions. Diagnosis of malaria still ...

Malaria, often referred to as "the King of Diseases", is the single largest cause of disease and death every year in tropical countries. It is possible to prevent malaria infections if those concerned (travelers to, and ...

Giemsa microscopy has played a major role in malaria control as a standard or reference method in diagnosis. However, this technique has varied performance characteristics while other techniques are more expensive. As a ...

Malaria and HIV/AIDS have a wide geographical overlap in several tropical regions. This makes co-infection of the two diseases very common. Due to enhanced global coverage of antiretroviral drugs (ARVs), HIV/AIDS patients ...

Malaria remains a major public health problem affecting an estimated 40% of the world’s population and resulting in more than 650,000 deaths worldwide every year. The emergence and rapid spread of parasite resistance to ...