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Immune Complex Levels in Children with Severe Plasmodium Falciparum Malaria.

Mibei, Erick Kipsang; Orago, A. S.; Stoute, J. A. (The American Society of Tropical Medicine, 2000-05)

Malaria infection leads to the formation of circulating immune complexes. However, it is unclear whether these complexes play a role in the pathogenesis of complicated Plasmodium falciparum malaria. This study aimed at ...

The levels of CD16/Fc gamma receptor IIIA on CD14+ CD16+ monocytes are higher in children with severe Plasmodium falciparum anemia than in children with cerebral or uncomplicated malaria.

Ogonda, Frederick L. A.; Orago, A. S.; Otieno, M.; Adhiambo, C.; Otieno, W.; Stoute, J. A. (PubMed, 2010)

Fc gamma receptor IIIA (CD16/Fc gamma RIIIA) on monocytes/macrophages may play an important role in the pathogenesis of severe malarial anemia (SMA) by promoting phagocytosis of IgG-coated uninfected red cells and by ...

Patient related barriers to adequate blood pressure control among adult hypertensive patients seen at Kiambu County Hospital, Kenya

Kibore Mogondo, Antony; Moturi, George; Thigiti, Joseph (East and Central Africa Medical Journal, 2020)

Introduction: Hypertension is a key precursor to cardiovascular and renal disease globally. According to WHO, Prevalence of hypertension was about 40 % globally in 2015 and 45% in Sub Saharan Africa in 2015. Despite much ...

Distinct Pattern of Class and Subclass Antibodies in Immune Complexes of Children with Cerebral Malaria and Severe Malarial Anaemia.

Mibei, Erick Kipsang; Otieno, W. O.; Orago, A. S.; Stoute, J. A. (Parasite Immunology Journal, 2008)

Plasmodium falciparum infection can lead to deadly complications such as severe malaria-associated anaemia (SMA) and cerebral malaria (CM). Children with severe malaria have elevated levels of circulating immune complexes ...