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In Vitro and in Vivo Antileishmanial Efficacy of a Combination Therapy of Diminazene and Artesunate against Leishmania Donovani in BALB/c Mice.

Gicheru, M. M.; Mutiso, J. M.; Macharia, J. C.; Barasa, M.; Taracha, E.; Bourdichon, A. J. (PubMed, 2011)

The in vitro and in vivo activity of diminazene (Dim), artesunate (Art) and combination of Dim and Art (Dim-Art) against Leishmania donovani was compared to reference drug; amphotericin B. IC50 of Dim-Art was found to be ...

Safety and Skin Delayed-type Hypersensitivity Response in Vervet Monkeys Immunized with Leishmania Donovani Sonicate Antigen Delivered with Adjuvants

Mutiso, J. M.; Macharia, J. C.; Taracha, E.; Wafula, K.; Rikoi, H.; Gicheru, M. M. (Institute of Primate Research, 2013-01)

In this study, we report on the safety and skin delayed-type hypersensitivity (DTH), responses of the Leishmania donovani whole cell sonicate antigen delivered in conjunction with alum-BCG (AlBCG), Montanide ISA 720 (MISA) ...