Search

Now showing items 1-6 of 6

Drug Recovery: Effect of Astemizole - Methylene Blue Combination Therapy against Plasmodium Strains in vitro

Nyirongo, Joyce; Kamau, Lucy; Simbauni, Jemimah A.; Mwangi, Victor; Kagasi, Esther; Onditi, Faith; Ozwara, Hastings (South Asian Journal of Parasitology, 2020)

Plasmodium species are protozoa from the Apicomplexa phylum which cause malaria. In the tropics and sub-tropics, approximately 3.3 billion people are threatened by this disease. Artemisinin Combination Therapy, has been ...

Plasmodium falciparum malaria disease manifestations in humans and transmission to Anopheles gambiae: a field study in Western Kenya

Kabiru, Ephantus W.; Gouagna, L. C.; Ferguson, H. M.; Okech, B. A.; Killeen, G. F.; Beier, J. C.; Githure, J. I.; Yan, G. (Cambridge University Press, 2004-03)

Transmission of the malaria parasite Plasmodium is influenced by many different host, vector and parasite factors. Here we conducted a field study at Mbita, an area of endemic malaria in Western Kenya, to test whether ...

Low exposure to Plasmodium falciparum and Acquisition of Antibodies to Circumsporozoite Protein Antigens in Individuals Living in Western Highlands of Kenya with Unstable Malaria Transmission

Walukhua, Michael Kisongochi; Gicheru, Michael M; Nyukuri, Robert Wanjala (East Africa Health Research Commission, 2020)

Background: Malaria continues to be a major public health concern despite the concerted efforts to eliminate it. Antibodies to Plasmodium falciparum (P. falciparum) antigens are involved in prevention of infection and ...

Naturally acquired immunoglobulin (Ig)G subclass antibodies to crude asexual Plasmodium falciparum lysates: evidence for association with protection for IgG1 and disease for IgG2

Kabiru, Ephantus W.; Ndungu, F. M.; Bull, P. C.; Ross, A.; Lowe, B. S.; Marsh, K. (Wiley, 2002-02)

There is longstanding evidence for a role of immunoglobulin (Ig)G in protection against malarial disease and infection. IgG1 and IgG3 have been shown to be particularly efficient at associating with monocytes in potentially ...

Rubia Cordifolia L. Crude Aerial Part Extracts Show a High Potential as Antimalarials against Chloroquine Resistant Plasmodium Falciparum Strains In Vitro

Jeremiah, Magara; Kamau, Lucy; Nyambati, Grace; Ozwara, Hastings (Pharmacognosy Research, 2023)

Introduction: Plasmodium falciparum human malaria parasite is resistant to most available medicines in Africa, necessitating research for new drugs. Rubia cordifolia L. is used in traditional malaria treatment in Kenya ...

Status of Plasmodium Falciparum Resistance to Sulfadoxine Pyrimethamine in Kwale County, Kenya

Mutwiri, Winfred Kendi; Gicheru, Michael; Kasili, Sichangi; Kimani, Francis T; Makokha, Francis (Advanced Research publication, 2019)

Background: Malaria persists to be one of the major significant diseases in the world. A range of antimalarial drugs are readily accessible but management of the disease remains a problem. Despite the broadened spread ...