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Immunopathological Features Developing in the Mosquito Midgut after Feeding on Anopheles gambiae Mucin-1 / Interleukin-12 cDNA Immunized Mice

Gicheru, M. M.; Kabiru, Ephantus W.; Githure, J. I.; Injera, Wilfred E.; Beier, John C. (Sociedad Chilena de Anatomía, 2013)

The mosquito midgut is the organ into which the blood meal passes and in which, within a peritrophic membrane secreted by the epithelium, the blood is retained during digestion and absorption. The mosquito midgut is lined ...

Distribution, Description, and Local Knowledge of Larval Habitats of Anopheles gambiae s.l. in a Village in Western Kenya.

Mutuku, F. M.; Alaii, J. A.; Bayoh, M. N.; Gimnig, J. E.; Vulule, J. M.; Walker, E. D.; Kabiru, Ephantus W.; Hawley, W. A. (The American Journal of Tropical Medicine and Hygiene, 2006-01)

A sampling census revealed 104 aquatic habitats of 6 types for Anopheles gambiae s.l. larvae in a village in western Kenya, namely burrow pits, drainage channels, livestock hoof prints, rain pools, tire tracks, and pools ...

Plasmodium falciparum malaria disease manifestations in humans and transmission to Anopheles gambiae: a field study in Western Kenya

Kabiru, Ephantus W.; Gouagna, L. C.; Ferguson, H. M.; Okech, B. A.; Killeen, G. F.; Beier, J. C.; Githure, J. I.; Yan, G. (Cambridge University Press, 2004-03)

Transmission of the malaria parasite Plasmodium is influenced by many different host, vector and parasite factors. Here we conducted a field study at Mbita, an area of endemic malaria in Western Kenya, to test whether ...

Effects of soil- transmitted helminths and schistosoma species on nutritional status of children in Mwea Irrigation Scheme, Kenya

Njiru, J.M.; Muhoho, N.; Simbauni, Jemimah A.; Kabiru, Ephantus W. (Sciencedomain International, 2016-04)

Aim: Soil- transmitted helminths (STH) and schistosomiasis are a major public health problem in Kenya as well as in many other tropical countries. Intestinal parasite infections have been associated with malabsorption ...

Concomitant Infections of Plasmodium Falciparum and Wuchereria Bancrofti on the Kenyan Coast

Kabiru, Ephantus W.; Muturi, E. J.; Mbogo, C. M.; Mwangangi, J. M.; Ng'ang'a, Z. W.; Mwandawiro, C.; Beier, J. C. (BioMed Central, 2006)

Background Anopheles gambiae s.l. and An. funestus are important vectors of malaria and bancroftian filariasis, which occur as co-endemic infections along the Kenyan Coast. However, little is known about the occurrence ...

Pupal Habitat Productivity of Anopheles gambiae Complex Mosquitoes in a Rural Village in Western Kenya.

Mutuku, F. M.; Bayoh, M. N.; Gimnig, J. E.; Vulule, J. M.; Kamau, L. M.; Walker, E. D.; Kabiru, Ephantus W.; Hawley, W. A. (The American journal of tropical medicine and hygiene, 2006)

The productivity of larval habitats of the malaria vector Anopheles gambiae for pupae (the stage preceding adult metamorphosis) is poorly known, yet adult emergence from habitats is the primary determinant of vector density. ...

Mosquitocidal Immune Response in BALB/c Mice Is Enhanced When Anopheles gambiae Mucin-1 cDNA Is Co-Administered with Interleukin-12 cDNA

Injera, W. E.; Foy, B. D.; Kabiru, Ephantus W.; Gicheru, M. M.; Githure, J. I.; Beier, J. C. (Canadian Center of Science and Education, 2013-04)

The midgut of the malaria - transmitting mosquito, Anopheles gambiae, can be targeted by vaccine-induced host immune factors that kill the mosquito after it ingests immunized host blood. The An. gambiae mucin 1 protein ...

Naturally acquired immunoglobulin (Ig)G subclass antibodies to crude asexual Plasmodium falciparum lysates: evidence for association with protection for IgG1 and disease for IgG2

Kabiru, Ephantus W.; Ndungu, F. M.; Bull, P. C.; Ross, A.; Lowe, B. S.; Marsh, K. (Wiley, 2002-02)

There is longstanding evidence for a role of immunoglobulin (Ig)G in protection against malarial disease and infection. IgG1 and IgG3 have been shown to be particularly efficient at associating with monocytes in potentially ...

Influence of indoor microclimate and diet on survival of Anopheles gambiae s.s. (Diptera: Culicidae) in village house conditions in western Kenya

Okech, B. A.; Gouagna, L. C.; Knols, B. G. J.; Kabiru, Ephantus W.; Killeen, G. F.; Beier, J. C.; Yan, G.; Githure, J. I. (Cambridge University Press, 2004-09)

The survival of female Anopheles gambiae s.s. mosquitoes inside two village house types (grass-thatched and iron-roofed) was studied in relation to diet and ambient indoor microclimatic conditions. Two batches of 20–30, ...

Influence of Age and Previous Diet of Anopheles Gambiae on the Infectivity of Natural Plasmodium Falciparum Gametocytes from Human Volunteers.

Okech, Bernard A.; Gouagna, Louis C.; Kabiru, Ephantus W.; Beier, John C.; Yan, Guiyun; Githure, John I. (Oxford University Press, 2004-10-22)

The effect of age and dietary factors of Anopheles gambiae (Diptera: Culicidae) on the infectivity of natural Plasmodium falciparum parasites was studied. Mosquitoes of various ages (1–3, 4–7 and 8–11 day old) and those ...