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Complement utilization in children with severe plasmodium falciparum malaria
Complement system, an important component of the innate and adaptive immunity, is over activated during malaria infection. As a result, components of the cascade are utilized consumed and this has the potential to impair ...
Pyridoxal kinase activity in plasmodium falciparum and plasmodium berghei in vitro
Pyridoxal kinase (PLK: EC18.104.22.168) is an essential enzyme for cellular synthesis of proteins where it plays a central role in transamination reactions. PLK is required for biosynthesis of B-6 coenzyme in which it ...
The expression of LFA-1, MAC-1 and ICAM-1 on leucocytes from patients with uncomplicated and those with complicated plasmodium falciparum malaria
Malaria is a major cause of morbidity and mortality in sub-Saharan Africa. Most of the mortality is the result of severe infections that occur in a small proportion of individuals, mostly children and pregnant women. A ...
Prevalence of glucose-6- phosphate dehydrogenase deficiency in children enrolled in a malaria vaccine clinical trial in Western Kenya
Deficiency of Glucose-6-phosphate dehydrogenase (G6PD) is the most frequently encountered genetic abnormality of red blood cell (RBC) metabolism, and is estimated to affect over 200 million people worldwide. Malaria is ...
Evalutation of malaria infection in relation to age, residence and diagnosis of patients attending Kipsamoite dispendary, Nandi North District, Kenya
Malaria imposes a huge burden upon the health and economic development of tropical nations and has been identified as a major obstacle to sustainable development by the world's poorest regions. Diagnosis of malaria still ...
Clinical evaluation of flourescent in- situ hybridization (Fish) assay for malaria diagnosis
Giemsa microscopy has played a major role in malaria control as a standard or reference method in diagnosis. However, this technique has varied performance characteristics while other techniques are more expensive. As a ...