Observations Following Administration of Alloxan in the Common Carp Cyprinus Carpio (L.) Fed on Yellow Soybeans Glycine Max
Okelo, R. O.
Puramik, P. G.
Omollo, J. F.
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On the administration of a total dose of 1g/kg of alloxan to Cyprinus carpio (L.) fish in five divided doses, the pancreatic islets showed no histologic alteration from those of the normal control animals. The anticipated beta cells destruction and consequent hyperglycemia did not ensue. However, in the individuals fed soybean alone there was a significant rise in the serum blood sugar with a concomitantly very significant fall in the total serum cholesterol. A toxic effect on the liver and kidney as evidenced by localized lesions in these organs was apparent. It is suggested that the degenerative changes noticed in the liver are caused by the direct action of alloxan on the organ. The treatment had significant decrease in the total blood cholesterol level in common carp fed on pellets and soybeans (50:50).